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KMID : 0191120130280101522
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Journal of Korean Medical Science
2013 Volume.28 No. 10 p.1522 ~ p.1528
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Improvement of Dementia Screening Accuracy of Mini-Mental State Examination by Education-Adjustment and Supplementation of Frontal Assessment Battery Performance
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Kim Jee-Wook
Lee Dong-Young
Seo Eun-Hyun
Sohn Bo-Kyung
Park Shin-Young
Choo IL-Han
Youn Jong-Chul
Jhoo Jin-Hyeong
Kim Ki-Woong
Woo Jong-Inn
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Abstract
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This study aimed to investigate whether the demographic variable-adjustment and supplementation of Frontal Assessment Battery (FAB) score can improve the screening ability of Mini-Mental State Examination (MMSE) for dementia and its subtypes. Five hundred forty-one non-demented comparison (NC) and 474 dementia (320 Alzheimer's disease [AD]; 139 non-Alzheimer's disease dementia [NAD]; and 15 mixed AD-NAD dementia) individuals living in the community were included. Education-adjusted MMSE (MMSE-edu) score showed significantly better screening accuracy for overall dementia, AD, and NAD than MMSE raw score. FAB-supplemented MMSE (MMSE-FAB) score had significantly better screening ability for NAD, but not for overall dementia and AD, than MMSE raw score alone. Additional supplementation of FAB to MMSE-edu further increased the ability for overall dementia or NAD screening, but not for AD screening. Further education adjustment of MMSE-FAB also improved its ability for overall dementia, AD, and NAD screening. These results strongly support the usefulness of education-adjustment and supplementation of frontal function assessment to improve screening performance of MMSE for dementia and its subtypes, NAD in particular.
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KEYWORD
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Mini-Mental State Examination, Frontal Assessment Battery, Education, Dementia, Screening Accuracy
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